Figure 1From: An impulsive mathematical model of bone formation and resorption: effects of parathyroid hormone, calcitonin and impulsive estrogen supplement Numerical simulation of equations (4a)-(4d). The solution trajectory approaches oscillatory solution \((0,\tilde {w}(t))\) as time passes. Here, all parameters are chosen to satisfy the conditions in Theorem 1, i.e., \({a_{1}}=0.65\), \({a_{2}}=0.3\), \({a_{3}}=0.3\), \({a_{4}}=0.9\), \({a_{5}}=0.1\), \({b_{1}}=0.5\), \({b_{2}}=0.2\), \({b_{3}}=0.425\), \({b_{4}}=0.5\), \({k_{1}}=0.1\), \({k_{2}}=0.5\), \({k_{3}}=0.1\), \({k_{4}}=0.5\), \({k_{5}}=0.01\), \({k_{6}}=0.75\), \(\mu=0.1\), \(\rho=0.1\), \(T=1\), \(z(0)=0.0001\), and \(w(0)=0.0001\). (a) The solution trajectory projected on \((z,w)\)-plane. (b) The corresponding time course of the number of active osteoclasts \((z)\) tending towards zero. (c) The corresponding time course of the number of active osteoblasts \((w)\) exhibiting positive oscillation.Back to article page