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Theory and Modern Applications

Table 2 Parametric values used in the model simulations shown in Figures  3 - 5

From: Modeling fibrous cap formation in atherosclerotic plaque development: stability and oscillatory behavior

Parameter

Meaning

Value (Figures  3 , 4 )

Value (Figure  5 )

Unit

\(d_{1}\)

Reaction rate constant in (1)

1.520 × 104

1.520 × 103

\(\mbox{g}^{-1}~\mbox{cm}^{3}~\mbox{wk}^{-1}\)

\(d_{2}\)

Variation constant in (2)

1.429

0.8024

\(\mbox{g}^{-1}~\mbox{cm}^{3}~\mbox{wk}^{-1}\)

\(d_{O}\)

Degradation rate of \(L_{O}\)

6.048 × 10−1

0.01

wk−1

\(d_{M}\)

Death rate of M

6.048 × 10−1

0.01

wk−1

\(d_{F}\)

Death rate of F

4.285 × 10−3

0.25

wk−1

\(d_{C}\)

Degradation rate of \(C_{O}\)

0.01

0.01

wk−1

\(d_{c}\)

Degradation rate of \(C_{M}\)

0.01

0.1

wk−1

\(d_{S}\)

Intrinsic death rate of S

1.08

0.1

wk−1

\(d_{E}\)

Removal rate of E

0.5

0.05

wk−1

\(k_{c}\)

Saturation constant of migration

10−4

10−2

wk−1

\(m_{s}\)

Removal rate of S to form E

1.68

0.5

wk−1

\(s_{1}\)

Production rate of \(C_{O}\)

6.05 × 10−3

1.520 × 103

wk−1

\(s_{2}\)

Immigration rate of M fostered by \(C_{O}\)

10.2

0.8024

wk−1

\(s_{3}\)

Production rate of \(C_{M}\)

0.1814

0.01

wk−1

\(s_{4}\)

Proportionality constant in production rate of S due to migration

1.814

0.01

wk−1

\(s_{5}\)

Variation constant in production rate of E

6.0

0.25

wk−1

\(R_{f}\)

Number of free radicals in oxidation process

0.02772

0.01

mg/ml

α

Fraction of \(M L_{O}\) that goes into E production

0.5

0.6

-

β

Fraction of \(M L_{O}\) that goes into F production

0.5

0.4

-

μ

Proportionality constant in (8)

6.05

0.00238

wk−1

ρ

Migration rate of S at vanishing \(C_{M}\)

7.5

0.001

\(\mbox{g}^{-1}~\mbox{cm}^{-3}~\mbox{wk}^{-1}\)

σ

Growth rate of \(L_{l}\)

2.016 × 103

2.016 × 103

\(\mbox{g}^{-1}~\mbox{cm}^{-3}~\mbox{wk}^{-1}\)

p

Proliferation rate of S

[1.700,1.765]

0.4

wk−1