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Theory and Modern Applications

Table 1 The description of parameters

From: Mathematical modeling of the immune-chemotherapeutic treatment of breast cancer under some control parameters

Parameter

Symbol

Value

Unit

The growth rate of NC

\(r_{1}\)

0.3

day−1

The growth rate of TC

\(r_{2}\)

0.4

day−1

Logistic rate of NC

\(\mu _{1}\)

[0.05–0.2]

day−1

Logistic rate of TC

\(\mu _{2}\)

[0.5–0.95]

day−1

Logistic rate of IC

\(\mu _{3}\)

[0.05–0.2]

day−1

Carrying capacity of NC

\(K_{1}\)

1.232

day−1

Carrying capacity of TC

\(K_{2}\)

1.75

day−1

Carrying capacity of IC

\(K_{3}\)

[0.11, 1.17]

day−1

Constant rate of the ketogenic diet

d

0.5

day−1

Rate of inhibition of NC

\(\beta _{1}\)

6 × 10−8

day−1

TC death rate due to immune response

\(\beta _{2}\)

3 × 10−6

day−1

Interaction coefficient rate with immune response

\(\beta _{3}\)

1 × 10−7

day−1

The natural death rate of estrogen

\(\beta _{4}\)

0.97

day−1

Tumor formation rate as a result of DNA damage by excess estrogen

\(\phi _{1}\)

0.2

day−1

Immune suppression rate due to excess estrogen

\(\phi _{2}\)

0.002

day−1

Efficacy of the anti-cancer drug

k

0–1

day−1

Source rate of IC

ρ

1.3 × 102

day−1

Supplement of immune booster

γ

0.01

day−1

The death rate of TC due to the ketogenic diet

δ

2

day−1

Source rate of estrogen

ε

[0.6–3]

day−1