Skip to main content

Theory and Modern Applications

Table 1 Biological significance of variables and parameters

From: The global dynamics in a wild-type and drug-resistant HIV infection model with saturated incidence

Variable/Parameter

Description

T(t)

concentrations of uninfected target cells at time t

\(T_{s}{(t)}\)

concentrations of cells productively infected by wild-type virus at time t

\(T_{r}{(t)}\)

concentrations of cells productively infected by drug-resistant virus at time t

\(V_{s}{(t)}\)

concentrations of wild-type virus at time t

\(V_{r}(t)\)

concentrations of drug-resistant virus at time t

λ

recruitment rate of uninfected cells

d

death rate of uninfected cells

\(k_{s}\)

infection rate of target cells by wild-type virus

\(k_{r}\)

infection rate of target cells by drug-resistant virus

δ

death rate of infected cells

\(N_{s}\)

burst size of wild-type strain

\(N_{r}\)

burst size of drug-resistant strain

c

clearance rate of free virus